Vegan diets can provide many health benefits, but some nutrients are harder to obtain from plants alone. This concise guide reviews five evidence-based vegan supplements that address common gaps and often come in palatable forms. For an overview from a specialist retailer, see [Topvitamine overview of vegan supplements](https://www.topvitamine.com/blogs/news/top-5-vegan-supplements-that-actually-work-and-taste-great-topvitamine). 1. Vitamin B12 Vitamin B12 is necessary for nerve function and red blood cell formation. Since reliable dietary B12 is scarce in unfortified plant foods, supplementation is generally recommended for strict vegans. Methylcobalamin and cyanocobalamin are common forms; methylcobalamin may offer better tissue uptake in some individuals. Many vegan-friendly options come as flavored sublingual tablets, chewables, or drops that mask any medicinal taste. 2. Omega-3 (Algal Oil) Long-chain omega-3 fatty acids (EPA and DHA) support cognitive health and cardiovascular function. Algal oil is the direct plant-based source of DHA and EPA and lacks the contaminants that can be present in fish oil. Algal oil supplements are available in softgels and emulsified liquids; flavored formulations can reduce any sea-like notes and improve acceptability. 3. Iron Plant-based diets can be lower in heme iron, which is more bioavailable than non-heme iron from plants. Vegan supplements commonly use well-absorbed, stomach-friendly forms such as ferrous bisglycinate or iron chelates. Powdered blends and chewable tablets often include natural fruit flavors and vitamin C to enhance absorption and mask metallic taste. 4. Vitamin D Vitamin D supports bone health and immune regulation; seasonal low sun exposure makes supplementation prudent for many people. Vegan sources include D2 from yeast and plant sources and D3 derived from lichen. Choose a form with verified potency and consider regular blood testing when appropriate. For comparison of D2 versus D3 and how to choose, consult Vitamin D2 vs Vitamin D3: key differences. 5. Probiotics Strains with documented benefits can support digestion and immune function. Vegan probiotic supplements avoid dairy carriers and frequently come in vegetarian capsules or powdered mixes that dissolve in water or smoothies, often with mild, pleasant flavors to improve routine use. How to choose Look for clear labeling of 100% plant-based ingredients, third-party verification (for potency and purity), and transparent source information. Consider nutrient forms with stronger evidence for absorption (for example, methylcobalamin for B12, ferrous bisglycinate for iron) and delivery formats you’ll reliably use. For guidance on how a multivitamin can fit into a plant-based diet, see Multivitamins: science-backed benefits and facts. Practical notes Taste and format matter for adherence: gummies, chewables, flavored powders, and sublingual drops can make daily supplementation more consistent. If you have medical conditions or take medications, consult a healthcare professional before starting new supplements. Summary Addressing common nutrient shortfalls with thoughtfully chosen vegan supplements—such as B12, algal omega-3s, iron, vitamin D, and probiotics—can support nutritional adequacy and well-being. Verify sources, prefer evidence-backed nutrient forms, and select formats that encourage consistent use. For additional context from a specialist perspective, see Topvitamine home.